La Guita isthemanzanilla from Sanlucar and the most popular wine in the region. Aged under highly active flor for four and a half years, La Guita develops intense complexity while retaining beautiful freshness. They bottle six times a year, as opposed to once or twice as many other houses, to capture as much freshness as possible.

La Guita is made in two bodegas, and the smaller of the two, Bodega Misericordia, dates to 1526. Located in the heart of Sanlcar, it was once the Hospital de San Juan de Dios. The larger bodega, Pago Sancular Viejo, is located on the road to Jerez and accounts for about 80% of La Guitas production. While legally allowed to source grapes from anywhere in Jerez, they focus exclusively on grapes from Sanlcar specifically from the Milaflores vineyard.